IL-33 promotes food anaphylaxis in epicutaneously-sensitized mice by targeting mast cells

BACKGROUND: Cutaneous exposure to food allergens predisposes to food allergy, which is commonly associated with atopic dermatitis (AD). The levels of the epithelial cytokine IL-33 are increased in skin lesions and serum of AD patients. Mast cells (MC) play a critical role in food anaphylaxis and exp...

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Publicado no:J Allergy Clin Immunol
Main Authors: Galand, Claire, Leyva-Castillo, Juan Manuel, Yoon, Juhan, Han, Alex, Lee, Margaret S., McKenzie, Andrew, Stassen, Michael, Oyoshi, Michiko K., Finkelman, Fred D., Geha, Raif S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5099088/
https://ncbi.nlm.nih.gov/pubmed/27372570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2016.03.056
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