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Mast cell-derived IL-13 downregulates IL-12 production by skin dendritic cells to inhibit the Th1 response to cutaneous antigen exposure.
BACKGROUND: Atopic dermatitis (AD) is characterized by a skin barrier defect, aggravated by mechanical injury inflicted by scratching, a Th2-dominated immune response and susceptibility to viral skin infections normally restrained by a Th1 response. The signals leading to a Th2-dominated immune resp...
Tallennettuna:
| Julkaisussa: | J Allergy Clin Immunol |
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| Päätekijät: | , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2020
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8184568/ https://ncbi.nlm.nih.gov/pubmed/33316284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2020.11.036 |
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