Epicutaneous sensitization results in IgE-dependent intestinal mast cell expansion and food anaphylaxis

BACKGROUND: Sensitization to food antigen may occur through cutaneous exposure. OBJECTIVE: Test the hypothesis that epicutaneous (EC) sensitization with food antigen predisposes to IgE-mediated anaphylaxis upon oral allergen challenge. METHODS: BALB/c mice were EC sensitized by repeated application...

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Detalhes bibliográficos
Main Authors: Bartnikas, Lisa M., Gurish, Michael F., Burton, Oliver T., Leisten, Sabine, Janssen, Erin, Oettgen, Hans C., Beaupré, Jacqueline, Lewis, Christopher N., Austen, K. Frank, Schulte, Stephanie, Hornick, Jason L., Geha, Raif S., Oyoshi, Michiko K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587010/
https://ncbi.nlm.nih.gov/pubmed/23374269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2012.11.032
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