Mechanical skin injury promotes food anaphylaxis by driving intestinal mast cell expansion.

Mast cell (MC) mediator release following crosslinking of surface-bound IgE antibody by ingested antigen underlies food allergy. However, IgE antibodies are not uniformly associated with food allergy, and intestinal MC load is an important determinant. Atopic dermatitis (AD), characterized by prurit...

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Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Leyva-Castillo, Juan-Manuel, Galand, Claire, Kam, Christy, Burton, Oliver, Gurish, Michael, Musser, Melissa A., Goldsmith, Jeffrey D., Hait, Elizabeth, Nurko, Samuel, Brombacher, Frank, Dong, Chen, Finkelman, Fred D., Lee, Richard T., Ziegler, Steven, Chiu, Isaac, Austen, K. Frank, Geha, Raif S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6531322/
https://ncbi.nlm.nih.gov/pubmed/31027995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2019.03.023
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