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IL-22 promotes allergic airway inflammation in epicutaneously sensitized mice

BACKGROUND: Serum IL-22 levels are elevated in atopic dermatitis (AD), which commonly precedes asthma in the atopic march. Epicutaneous (EC) sensitization in mice results in Th2-dominated skin inflammation that mimics AD, and sensitizes the airways for antigen challenge-induced allergic inflammation...

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Bibliografische gegevens
Gepubliceerd in:J Allergy Clin Immunol
Hoofdauteurs: Leyva-Castillo, Juan Manuel, Yoon, Juhan, Geha, Raif S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6298864/
https://ncbi.nlm.nih.gov/pubmed/29920352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2018.05.032
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