IL-21R is essential for epicutaneous sensitization and allergic skin inflammation in humans and mice

Atopic dermatitis (AD) is a common allergic inflammatory skin disease caused by a combination of intense pruritus, scratching, and epicutaneous (e.c.) sensitization with allergens. To explore the roles of IL-21 and IL-21 receptor (IL-21R) in AD, we examined skin lesions from patients with AD and use...

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Main Authors: Jin, Haoli, Oyoshi, Michiko K., Le, Yi, Bianchi, Teresa, Koduru, Suresh, Mathias, Clinton B., Kumar, Lalit, Le Bras, Séverine, Young, Deborah, Collins, Mary, Grusby, Michael J., Wenzel, Joerg, Bieber, Thomas, Boes, Marianne, Silberstein, Leslie E., Oettgen, Hans C., Geha, Raif S.
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2008
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613448/
https://ncbi.nlm.nih.gov/pubmed/19075398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32310
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