IL-21R is essential for epicutaneous sensitization and allergic skin inflammation in humans and mice

Atopic dermatitis (AD) is a common allergic inflammatory skin disease caused by a combination of intense pruritus, scratching, and epicutaneous (e.c.) sensitization with allergens. To explore the roles of IL-21 and IL-21 receptor (IL-21R) in AD, we examined skin lesions from patients with AD and use...

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Bibliografische gegevens
Hoofdauteurs: Jin, Haoli, Oyoshi, Michiko K., Le, Yi, Bianchi, Teresa, Koduru, Suresh, Mathias, Clinton B., Kumar, Lalit, Le Bras, Séverine, Young, Deborah, Collins, Mary, Grusby, Michael J., Wenzel, Joerg, Bieber, Thomas, Boes, Marianne, Silberstein, Leslie E., Oettgen, Hans C., Geha, Raif S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2008
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613448/
https://ncbi.nlm.nih.gov/pubmed/19075398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32310
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