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An efficient route to bispecific antibody production using single-reactor mammalian co-culture
Bispecific antibodies have shown promise in the clinic as medicines with novel mechanisms of action. Lack of efficient production of bispecific IgGs, however, has limited their rapid advancement. Here, we describe a single-reactor process using mammalian cell co-culture production to efficiently pro...
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| Pubblicato in: | MAbs |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5098433/ https://ncbi.nlm.nih.gov/pubmed/27680183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2016.1234569 |
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