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An efficient route to bispecific antibody production using single-reactor mammalian co-culture
Bispecific antibodies have shown promise in the clinic as medicines with novel mechanisms of action. Lack of efficient production of bispecific IgGs, however, has limited their rapid advancement. Here, we describe a single-reactor process using mammalian cell co-culture production to efficiently pro...
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Publicado no: | MAbs |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Taylor & Francis
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5098433/ https://ncbi.nlm.nih.gov/pubmed/27680183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2016.1234569 |
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