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Unliganded Fibroblast Growth Factor Receptor 1 Forms Density-independent Dimers

Fibroblast growth factors receptors (FGFRs) are thought to initiate intracellular signaling cascades upon ligand-induced dimerization of the extracellular domain. Although the existence of unliganded FGFR1 dimers on the surface of living cells has been proposed, this notion remains rather controvers...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Comps-Agrar, Laëtitia, Dunshee, Diana Ronai, Eaton, Dan L., Sonoda, Junichiro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4591805/
https://ncbi.nlm.nih.gov/pubmed/26272615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.681395
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