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Amelioration of EAE by a Cryptic Epitope of Myelin Oligodendrocyte Glycoprotein
Previous work demonstrated that EAE induced by recombinant human MOG was B cell-dependent. Data presented here reveal a T cell response to MOG61-85 in human rMOG-immunized B cell(−/−) mice not observed in WT mice. Further study revealed this peptide to be a cryptic epitope in WT mice. Co-immunizatio...
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| Publicado en: | J Neuroimmunol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5097007/ https://ncbi.nlm.nih.gov/pubmed/27423965 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2016.06.006 |
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