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Amelioration of EAE by a Cryptic Epitope of Myelin Oligodendrocyte Glycoprotein

Previous work demonstrated that EAE induced by recombinant human MOG was B cell-dependent. Data presented here reveal a T cell response to MOG61-85 in human rMOG-immunized B cell(−/−) mice not observed in WT mice. Further study revealed this peptide to be a cryptic epitope in WT mice. Co-immunizatio...

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Foilsithe in:J Neuroimmunol
Main Authors: Lyons, Jeri A., Riter, Melissa M., Almatrook, Alaa M., Ramsbottom, Michael J., Cross, Anne H.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5097007/
https://ncbi.nlm.nih.gov/pubmed/27423965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2016.06.006
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