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B cells limit epitope spreading and reduce severity of EAE induced with PLP peptide in BALB/c mice

The role of B cells and antibody in Experimental Autoimmune Encephalomyelitis (EAE) appears to differ based on the identity and state (protein vs. encephalitogenic peptide) of the inducing antigen and the strain of mouse utilized. The involvement of B cells in the induction of EAE by peptides of pro...

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Detalhes bibliográficos
Main Authors: Lyons, Jeri-Anne, Ramsbottom, Michael J., Mikesell, Robert J., Cross, Anne H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2580779/
https://ncbi.nlm.nih.gov/pubmed/18539432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2008.04.025
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