Ablation of the epithelial‐specific splicing factor Esrp1 results in ureteric branching defects and reduced nephron number

BACKGROUND: Abnormalities in ureteric bud (UB) branching morphogenesis lead to congenital anomalies of the kidney and reduced nephron numbers associated with chronic kidney disease (CKD) and hypertension. Previous studies showed that the epithelial fibroblast growth factor receptor 2 (Fgfr2) IIIb sp...

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Detalhes bibliográficos
Publicado no:Dev Dyn
Main Authors: Bebee, Thomas W., Sims‐Lucas, Sunder, Park, Juw Won, Bushnell, Daniel, Cieply, Benjamin, Xing, Yi, Bates, Carlton M., Carstens, Russ P.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5096029/
https://ncbi.nlm.nih.gov/pubmed/27404344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.24431
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