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Prorenin receptor is critical for nephron progenitors

Deficient nephrogenesis is the major factor contributing to renal hypoplasia defined as abnormally small kidneys. Nephron induction during kidney development is driven by reciprocal interactions between progenitor cells of the cap mesenchyme (CM) and the ureteric bud (UB). The prorenin receptor (PRR...

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Bibliographische Detailangaben
Veröffentlicht in:Dev Biol
Hauptverfasser: Song, Renfang, Preston, Graeme, Kidd, Laura, Bushnell, Daniel, Sims-Lucas, Sunder, Bates, Carlton M., Yosypiv, Ihor V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724493/
https://ncbi.nlm.nih.gov/pubmed/26658320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2015.11.024
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