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Conditional ablation of the prorenin receptor in nephron progenitor cells results in developmental programming of hypertension

Nephron induction during kidney development is driven by reciprocal interactions between progenitor cells (NPCs) of the cap mesenchyme (CM) and the ureteric bud (UB). The prorenin receptor (PRR) is a receptor for renin and prorenin, and an accessory subunit of the vacuolar proton pump V‐ATPase. Prev...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Song, Renfang, Kidd, Laura, Janssen, Adam, Yosypiv, Ihor V.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880790/
https://ncbi.nlm.nih.gov/pubmed/29611334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13644
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