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Conditional ablation of the prorenin receptor in nephron progenitor cells results in developmental programming of hypertension

Nephron induction during kidney development is driven by reciprocal interactions between progenitor cells (NPCs) of the cap mesenchyme (CM) and the ureteric bud (UB). The prorenin receptor (PRR) is a receptor for renin and prorenin, and an accessory subunit of the vacuolar proton pump V‐ATPase. Prev...

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Publicat a:Physiol Rep
Autors principals: Song, Renfang, Kidd, Laura, Janssen, Adam, Yosypiv, Ihor V.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880790/
https://ncbi.nlm.nih.gov/pubmed/29611334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13644
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