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Deletion of the Prorenin Receptor from the Ureteric Bud Causes Renal Hypodysplasia

The role of the prorenin receptor (PRR) in the regulation of ureteric bud (UB) branching morphogenesis is unknown. Here, we investigated whether PRR acts specifically in the UB to regulate UB branching, kidney development and function. We demonstrate that embryonic (E) day E13.5 mouse metanephroi, i...

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Hlavní autoři: Song, Renfang, Preston, Graeme, Ichihara, Atsuhiro, Yosypiv, Ihor V.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660567/
https://ncbi.nlm.nih.gov/pubmed/23704941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063835
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