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Deletion of the Prorenin Receptor from the Ureteric Bud Causes Renal Hypodysplasia

The role of the prorenin receptor (PRR) in the regulation of ureteric bud (UB) branching morphogenesis is unknown. Here, we investigated whether PRR acts specifically in the UB to regulate UB branching, kidney development and function. We demonstrate that embryonic (E) day E13.5 mouse metanephroi, i...

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書誌詳細
主要な著者: Song, Renfang, Preston, Graeme, Ichihara, Atsuhiro, Yosypiv, Ihor V.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660567/
https://ncbi.nlm.nih.gov/pubmed/23704941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063835
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