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Histone Deacetylases Are Critical Regulators of the Renin-Angiotensin System During Ureteric Bud Branching Morphogenesis

Mutations in the genes encoding components of the renin-angiotensin system (RAS) in mice or humans cause congenital abnormalities of the kidney and urinary tract. We hypothesized that absence of angiotensin (Ang) II in angiotensinogen (AGT)-deficient mice leads to defects in ureteric bud (UB) branch...

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Bibliographische Detailangaben
Hauptverfasser: SONG, RENFANG, VAN BUREN, THOMAS, YOSYPIV, IHOR V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039915/
https://ncbi.nlm.nih.gov/pubmed/20496471
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