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Angiotensin II-induced activation of c-Ret signaling is critical in ureteric bud branching morphogenesis

The renin-angiotensin system (RAS) plays a critical role in ureteric bud (UB) and kidney morphogenesis. Mutations in the genes encoding components of the RAS cause a spectrum of congenital abnormalities of the kidney and urinary tract (CAKUT). However, the mechanisms by which aberrations in the RAS...

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Autori principali: Song, Renfang, Spera, Melissa, Garrett, Colleen, Yosypiv, Ihor V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825703/
https://ncbi.nlm.nih.gov/pubmed/19961928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mod.2009.11.004
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