Ablation of the epithelial‐specific splicing factor Esrp1 results in ureteric branching defects and reduced nephron number

BACKGROUND: Abnormalities in ureteric bud (UB) branching morphogenesis lead to congenital anomalies of the kidney and reduced nephron numbers associated with chronic kidney disease (CKD) and hypertension. Previous studies showed that the epithelial fibroblast growth factor receptor 2 (Fgfr2) IIIb sp...

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Bibliografiske detaljer
Udgivet i:Dev Dyn
Main Authors: Bebee, Thomas W., Sims‐Lucas, Sunder, Park, Juw Won, Bushnell, Daniel, Cieply, Benjamin, Xing, Yi, Bates, Carlton M., Carstens, Russ P.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5096029/
https://ncbi.nlm.nih.gov/pubmed/27404344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.24431
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