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The number of fetal nephron progenitor cells limits ureteric branching and adult nephron endowment
Nephrons, the functional units of the kidney, develop from progenitor cells (cap mesenchyme, CM) surrounding the epithelial ureteric bud (UB) tips. Reciprocal signaling between UB and CM induces nephrogenesis and UB branching. While low nephron number is implicated in hypertension and renal disease,...
Tallennettuna:
| Päätekijät: | , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2014
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4049224/ https://ncbi.nlm.nih.gov/pubmed/24656820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.02.033 |
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