The splicing regulators Esrp1 and Esrp2 direct an epithelial splicing program essential for mammalian development

Tissue- and cell-type-specific regulators of alternative splicing (AS) are essential components of posttranscriptional gene regulation, necessary for normal cellular function, patterning, and development. Mice with ablation of Epithelial splicing regulatory protein (Esrp1) develop cleft lip and pala...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Bebee, Thomas W, Park, Juw Won, Sheridan, Katherine I, Warzecha, Claude C, Cieply, Benjamin W, Rohacek, Alex M, Xing, Yi, Carstens, Russ P
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2015
Assuntos:
Developmental Biology and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4566030/
https://ncbi.nlm.nih.gov/pubmed/26371508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.08954
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