Identification and Characterization of MCM3 as a Kelch-like ECH-associated Protein 1 (KEAP1) Substrate

KEAP1 is a substrate adaptor protein for a CUL3-based E3 ubiquitin ligase. Ubiquitylation and degradation of the antioxidant transcription factor NRF2 is considered the primary function of KEAP1; however, few other KEAP1 substrates have been identified. Because KEAP1 is altered in a number of human...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:J Biol Chem
Main Authors: Mulvaney, Kathleen M., Matson, Jacob P., Siesser, Priscila F., Tamir, Tigist Y., Goldfarb, Dennis, Jacobs, Timothy M., Cloer, Erica W., Harrison, Joseph S., Vaziri, Cyrus, Cook, Jeanette G., Major, Michael B.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2016
Ábhair:
Signal Transduction
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095425/
https://ncbi.nlm.nih.gov/pubmed/27621311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.729418
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla