Kidney epithelium specific deletion of kelch-like ECH-associated protein 1 (Keap1) causes hydronephrosis in mice

BACKGROUND: Transcription factor Nrf2 protects from experimental acute kidney injury (AKI) and is promising to limit progression in human chronic kidney disease (CKD) by upregulating multiple antioxidant genes. We recently demonstrated that deletion of Keap1, the endogenous inhibitor of Nrf2, in T l...

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Bibliografische gegevens
Gepubliceerd in:BMC Nephrol
Hoofdauteurs: Noel, Sanjeev, Arend, Lois J., Bandapalle, Samatha, Reddy, Sekhar P., Rabb, Hamid
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2016
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4969727/
https://ncbi.nlm.nih.gov/pubmed/27484495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12882-016-0310-y
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