Kidney epithelium specific deletion of kelch-like ECH-associated protein 1 (Keap1) causes hydronephrosis in mice

BACKGROUND: Transcription factor Nrf2 protects from experimental acute kidney injury (AKI) and is promising to limit progression in human chronic kidney disease (CKD) by upregulating multiple antioxidant genes. We recently demonstrated that deletion of Keap1, the endogenous inhibitor of Nrf2, in T l...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:BMC Nephrol
Päätekijät: Noel, Sanjeev, Arend, Lois J., Bandapalle, Samatha, Reddy, Sekhar P., Rabb, Hamid
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2016
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4969727/
https://ncbi.nlm.nih.gov/pubmed/27484495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12882-016-0310-y
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