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Methods for the Isolation, Culture, and Functional Characterization of Sinoatrial Node Myocytes from Adult Mice

Sinoatrial node myocytes (SAMs) act as the natural pacemakers of the heart, initiating each heart beat by generating spontaneous action potentials (APs). These pacemaker APs reflect the coordinated activity of numerous membrane currents and intracellular calcium cycling. However the precise mechanis...

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Bibliografiske detaljer
Udgivet i:J Vis Exp
Main Authors: Sharpe, Emily J., St. Clair, Joshua R., Proenza, Catherine
Format: Artigo
Sprog:Inglês
Udgivet: MyJove Corporation 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5092239/
https://ncbi.nlm.nih.gov/pubmed/27805586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/54555
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