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Depressed pacemaker activity of sinoatrial node myocytes contributes to the age-dependent decline in maximum heart rate
An inexorable decline in maximum heart rate (mHR) progressively limits human aerobic capacity with advancing age. This decrease in mHR results from an age-dependent reduction in “intrinsic heart rate” (iHR), which is measured during autonomic blockade. The reduced iHR indicates, by definition, that...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3816448/ https://ncbi.nlm.nih.gov/pubmed/24128759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1308477110 |
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