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Methods for the Isolation, Culture, and Functional Characterization of Sinoatrial Node Myocytes from Adult Mice

Sinoatrial node myocytes (SAMs) act as the natural pacemakers of the heart, initiating each heart beat by generating spontaneous action potentials (APs). These pacemaker APs reflect the coordinated activity of numerous membrane currents and intracellular calcium cycling. However the precise mechanis...

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Détails bibliographiques
Publié dans:J Vis Exp
Auteurs principaux: Sharpe, Emily J., St. Clair, Joshua R., Proenza, Catherine
Format: Artigo
Langue:Inglês
Publié: MyJove Corporation 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5092239/
https://ncbi.nlm.nih.gov/pubmed/27805586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/54555
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