Immortalization of osteoclast precursors by targeting Bcl -XL and Simian virus 40 large T antigen to the osteoclast lineage in transgenic mice.

Cellular and molecular characterization of osteoclasts (OCL) has been extremely difficult since OCL are rare cells, and are difficult to isolate in large numbers. We used the tartrate-resistant acid phosphatase promoter to target the bcl-XL and/or Simian Virus 40 large T antigen (Tag) genes to cells...

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Detalhes bibliográficos
Main Authors: Hentunen, T A, Reddy, S V, Boyce, B F, Devlin, R, Park, H R, Chung, H, Selander, K S, Dallas, M, Kurihara, N, Galson, D L, Goldring, S R, Koop, B A, Windle, J J, Roodman, G D
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC509069/
https://ncbi.nlm.nih.gov/pubmed/9649561
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