Immortalization of osteoclast precursors by targeting Bcl -XL and Simian virus 40 large T antigen to the osteoclast lineage in transgenic mice.

Cellular and molecular characterization of osteoclasts (OCL) has been extremely difficult since OCL are rare cells, and are difficult to isolate in large numbers. We used the tartrate-resistant acid phosphatase promoter to target the bcl-XL and/or Simian Virus 40 large T antigen (Tag) genes to cells...

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Autori principali: Hentunen, T A, Reddy, S V, Boyce, B F, Devlin, R, Park, H R, Chung, H, Selander, K S, Dallas, M, Kurihara, N, Galson, D L, Goldring, S R, Koop, B A, Windle, J J, Roodman, G D
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1998
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC509069/
https://ncbi.nlm.nih.gov/pubmed/9649561
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