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TBK1 Mediates Critical Effects of Measles Virus Nucleocapsid Protein (MVNP) on Pagetic Osteoclast Formation

Paget’s disease of bone (PDB) is characterized by abnormal osteoclasts with unique characteristics that include: increased sensitivity of osteoclast progenitors to 1,25(OH)(2)D(3), RANKL and TNF-α, increased osteoclast numbers, increased expression of IL-6 and several transcription factors. We recen...

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Bibliografiske detaljer
Main Authors: Sun, Quanhong, Sammut, Bénédicte, Wang, Feng-Ming, Kurihara, Noriyoshi, Windle, Jolene J., Roodman, G. David, Galson, Deborah L.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870038/
https://ncbi.nlm.nih.gov/pubmed/23794264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2026
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