Red‐shifted channelrhodopsin stimulation restores light responses in blind mice, macaque retina, and human retina

Targeting the photosensitive ion channel channelrhodopsin‐2 (ChR2) to the retinal circuitry downstream of photoreceptors holds promise in treating vision loss caused by retinal degeneration. However, the high intensity of blue light necessary to activate channelrhodopsin‐2 exceeds the safety thresho...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:EMBO Mol Med
Päätekijät: Sengupta, Abhishek, Chaffiol, Antoine, Macé, Emilie, Caplette, Romain, Desrosiers, Mélissa, Lampič, Maruša, Forster, Valérie, Marre, Olivier, Lin, John Y, Sahel, José‐Alain, Picaud, Serge, Dalkara, Deniz, Duebel, Jens
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2016
Aiheet:
Research Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5090658/
https://ncbi.nlm.nih.gov/pubmed/27679671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201505699
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