Restoration of visual function by transplantation of optogenetically engineered photoreceptors

A major challenge in the treatment of retinal degenerative diseases, with the transplantation of replacement photoreceptors, is the difficulty in inducing the grafted cells to grow and maintain light sensitive outer segments in the host retina, which depends on proper interaction with the underlying...

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Published in:Nat Commun
Main Authors: Garita-Hernandez, Marcela, Lampič, Maruša, Chaffiol, Antoine, Guibbal, Laure, Routet, Fiona, Santos-Ferreira, Tiago, Gasparini, Sylvia, Borsch, Oliver, Gagliardi, Giuliana, Reichman, Sacha, Picaud, Serge, Sahel, José-Alain, Goureau, Olivier, Ader, Marius, Dalkara, Deniz, Duebel, Jens
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6778196/
https://ncbi.nlm.nih.gov/pubmed/31586094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12330-2
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