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Restoration of visual function by transplantation of optogenetically engineered photoreceptors

A major challenge in the treatment of retinal degenerative diseases, with the transplantation of replacement photoreceptors, is the difficulty in inducing the grafted cells to grow and maintain light sensitive outer segments in the host retina, which depends on proper interaction with the underlying...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Garita-Hernandez, Marcela, Lampič, Maruša, Chaffiol, Antoine, Guibbal, Laure, Routet, Fiona, Santos-Ferreira, Tiago, Gasparini, Sylvia, Borsch, Oliver, Gagliardi, Giuliana, Reichman, Sacha, Picaud, Serge, Sahel, José-Alain, Goureau, Olivier, Ader, Marius, Dalkara, Deniz, Duebel, Jens
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6778196/
https://ncbi.nlm.nih.gov/pubmed/31586094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12330-2
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