The amiloride-inhibitable Na+ conductance is reduced by the cystic fibrosis transmembrane conductance regulator in normal but not in cystic fibrosis airways.

Cystic fibrosis (CF) airway cells, besides their well-known defect in cAMP-dependent Cl- conductance, are characterized by an enhanced Na+ conductance. In this study we have examined the Na+ conductance in human respiratory tract by measuring transepithelial voltage and resistance (Vte, Rte) and by...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Mall, M, Bleich, M, Greger, R, Schreiber, R, Kunzelmann, K
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1998
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC509060/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9649552/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI2729
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