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Merosin-deficient congenital muscular dystrophy. Partial genetic correction in two mouse models.

Humans and mice with deficiency of the alpha2 subunit of the basement membrane protein laminin-2/merosin suffer from merosin-deficient congenital muscular dystrophy (MCMD). We have expressed a human laminin alpha2 chain transgene under the regulation of a muscle-specific creatine kinase promoter in...

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Main Authors: Kuang, W, Xu, H, Vachon, P H, Liu, L, Loechel, F, Wewer, U M, Engvall, E
Format: Artigo
Jezik:Inglês
Izdano: 1998
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC508948/
https://ncbi.nlm.nih.gov/pubmed/9710454
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