Effects of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors, atorvastatin and simvastatin, on the expression of endothelin-1 and endothelial nitric oxide synthase in vascular endothelial cells.

Endothelial dysfunction associated with atherosclerosis has been attributed to alterations in the L-arginine-nitric oxide (NO)-cGMP pathway or to an excess of endothelin-1 (ET-1). The 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) have been shown to ameliorate endothelial funct...

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Main Authors: Hernández-Perera, O, Pérez-Sala, D, Navarro-Antolín, J, Sánchez-Pascuala, R, Hernández, G, Díaz, C, Lamas, S
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1998
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC508862/
https://ncbi.nlm.nih.gov/pubmed/9637705
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