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The 3-hydroxy-3-methylglutaryl coenzyme-A (HMG-CoA) reductases

The enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase catalyzes the conversion of HMG-CoA to mevalonate, a four-electron oxidoreduction that is the rate-limiting step in the synthesis of cholesterol and other isoprenoids. The enzyme is found in eukaryotes and prokaryotes; and phylogen...

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Hlavní autoři: Friesen, Jon A, Rodwell, Victor W
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC545772/
https://ncbi.nlm.nih.gov/pubmed/15535874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2004-5-11-248
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