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Characterization and regulation of Leishmania major 3-hydroxy-3-methylglutaryl-CoA reductase.

In eukaryotes the enzyme 3-hydroxy-3-methylglutaryl CoA (HMG-CoA) reductase catalyses the synthesis of mevalonic acid, a common precursor to all isoprenoid compounds. Here we report the isolation and overexpression of the gene coding for HMG-CoA reductase from Leishmania major. The protein from Leis...

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Bibliografische gegevens
Hoofdauteurs: Montalvetti, A, Peña-Díaz, J, Hurtado, R, Ruiz-Pérez, L M, González-Pacanowska, D
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2000
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1221116/
https://ncbi.nlm.nih.gov/pubmed/10861207
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