Mitochondrial Localization of the Mevalonate Pathway Enzyme 3-Hydroxy-3-methyl-glutaryl-CoA Reductase in the Trypanosomatidae

3-Hydroxy-3-methyl-glutaryl-CoA reductase (HMGR) is a key enzyme in the sterol biosynthesis pathway, but its subcellular distribution in the Trypanosomatidae family is somewhat controversial. Trypanosoma cruzi and Leishmania HMGRs are closely related in their catalytic domains to bacterial and eukar...

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Detalhes bibliográficos
Main Authors: Peña-Diaz, Javier, Montalvetti, Andrea, Flores, Carmen-Lisset, Constán, Aurora, Hurtado-Guerrero, Ramon, De Souza, Wanderley, Gancedo, Carlos, Ruiz-Perez, Luis M., Gonzalez-Pacanowska, Dolores
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2004
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC363142/
https://ncbi.nlm.nih.gov/pubmed/14699057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-10-0720
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