Epigallocatechin-3-gallate potently inhibits the in vitro activity of hydroxy-3-methyl-glutaryl-CoA reductase

Hydroxy-3-methyl-glutaryl-CoA reductase (HMGR) is the rate-controlling enzyme of cholesterol synthesis, and owing to its biological and pharmacological relevance, researchers have investigated several compounds capable of modulating its activity with the hope of developing new hypocholesterolemic dr...

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מידע ביבליוגרפי
Main Authors: Cuccioloni, Massimiliano, Mozzicafreddo, Matteo, Spina, Michele, Tran, Chi Nhan, Falconi, Maurizio, Eleuteri, Anna Maria, Angeletti, Mauro
פורמט: Artigo
שפה:Inglês
יצא לאור: The American Society for Biochemistry and Molecular Biology 2011
נושאים:
Research Articles
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073461/
https://ncbi.nlm.nih.gov/pubmed/21357570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M011817
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