Epigallocatechin-3-gallate potently inhibits the in vitro activity of hydroxy-3-methyl-glutaryl-CoA reductase

Hydroxy-3-methyl-glutaryl-CoA reductase (HMGR) is the rate-controlling enzyme of cholesterol synthesis, and owing to its biological and pharmacological relevance, researchers have investigated several compounds capable of modulating its activity with the hope of developing new hypocholesterolemic dr...

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Bibliografiska uppgifter
Huvudupphovsmän: Cuccioloni, Massimiliano, Mozzicafreddo, Matteo, Spina, Michele, Tran, Chi Nhan, Falconi, Maurizio, Eleuteri, Anna Maria, Angeletti, Mauro
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Biochemistry and Molecular Biology 2011
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073461/
https://ncbi.nlm.nih.gov/pubmed/21357570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M011817
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