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The pleiotropic effects of the hydroxy-methyl-glutaryl-CoA reductase inhibitors in renal disease
It is well known that statins exert their main effect by inhibiting cholesterol synthesis through the inhibition of the 3-hydroxy-3-methyl-glutaryl-CoA reductase enzyme. The pleiotropic effects of statins, which are independent of their inhibition of cholesterol synthesis, have explained many of the...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3974687/ https://ncbi.nlm.nih.gov/pubmed/24729724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJNRD.S55102 |
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