Ubiquitin-mediated regulation of 3-hydroxy-3-methylglutaryl-CoA reductase
Regulation of the sterol-synthesizing mevalonate pathway occurs in part through feedback-regulated endoplasmic reticulum degradation of 3-hydroxy-3-methylglutaryl-CoA reductase (HMG-R). In yeast, the Hmg2p isozyme of HMG-R is regulated in this manner. We have tested the involvement of ubiquitination...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24243/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9371780/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.24.12944 |
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