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Ubiquitin-mediated regulation of 3-hydroxy-3-methylglutaryl-CoA reductase
Regulation of the sterol-synthesizing mevalonate pathway occurs in part through feedback-regulated endoplasmic reticulum degradation of 3-hydroxy-3-methylglutaryl-CoA reductase (HMG-R). In yeast, the Hmg2p isozyme of HMG-R is regulated in this manner. We have tested the involvement of ubiquitination...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The National Academy of Sciences of the USA
1997
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC24243/ https://ncbi.nlm.nih.gov/pubmed/9371780 |
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