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Dynamics of Thrombin Generation and Flux from Clots during Whole Human Blood Flow over Collagen/Tissue Factor Surfaces

Coagulation kinetics are well established for purified blood proteases or human plasma clotting isotropically. However, less is known about thrombin generation kinetics and transport within blood clots formed under hemodynamic flow. Using microfluidic perfusion (wall shear rate, 200 s(−1)) of corn t...

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Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Zhu, Shu, Lu, Yichen, Sinno, Talid, Diamond, Scott L.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087723/
https://ncbi.nlm.nih.gov/pubmed/27605669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.754671
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