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Dynamics of Thrombin Generation and Flux from Clots during Whole Human Blood Flow over Collagen/Tissue Factor Surfaces

Coagulation kinetics are well established for purified blood proteases or human plasma clotting isotropically. However, less is known about thrombin generation kinetics and transport within blood clots formed under hemodynamic flow. Using microfluidic perfusion (wall shear rate, 200 s(−1)) of corn t...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Zhu, Shu, Lu, Yichen, Sinno, Talid, Diamond, Scott L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087723/
https://ncbi.nlm.nih.gov/pubmed/27605669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.754671
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