Regulation of DNA replication and chromosomal polyploidy by the MLL-WDR5-RBBP5 methyltransferases

DNA replication licensing occurs on chromatin, but how the chromatin template is regulated for replication remains mostly unclear. Here, we have analyzed the requirement of histone methyltransferases for a specific type of replication: the DNA re-replication induced by the downregulation of either G...

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Библиографические подробности
Опубликовано в: :Biol Open
Главные авторы: Lu, Fei, Wu, Xiaojun, Yin, Feng, Chia-Fang Lee, Christina, Yu, Min, Mihaylov, Ivailo S., Yu, Jiekai, Sun, Hong, Zhang, Hui
Формат: Artigo
Язык:Inglês
Опубликовано: The Company of Biologists Ltd 2016
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087680/
https://ncbi.nlm.nih.gov/pubmed/27744293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.019729
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