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MLL1/WDR5 complex in leukemogenesis and epigenetic regulation

MLL1 is a histone H3Lys4 methyltransferase and forms a complex with WDR5 and other components. It plays important roles in developmental events, transcriptional regulation, and leukemogenesis. MLL1 -fusion proteins resulting from chromosomal translocations are molecular hallmarks of a special type o...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wu, Min, Shu, Hong-Bing
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Sun Yat-sen University Cancer Center 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013350/
https://ncbi.nlm.nih.gov/pubmed/21439245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5732/cjc.011.10055
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