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The internal interaction in RBBP5 regulates assembly and activity of MLL1 methyltransferase complex
The Mixed Lineage Leukemia protein 1 (MLL1) plays an essential role in the maintenance of the histone H3 lysine 4 (H3K4) methylation status for gene expression during differentiation and development. The methyltransferase activity of MLL1 is regulated by three conserved core subunits, WDR5, RBBP5 an...
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| 出版年: | Nucleic Acids Res |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6821195/ https://ncbi.nlm.nih.gov/pubmed/31544921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz819 |
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