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Simultaneous identification of specifically interacting paralogs and interprotein contacts by direct coupling analysis

Understanding protein−protein interactions is central to our understanding of almost all complex biological processes. Computational tools exploiting rapidly growing genomic databases to characterize protein−protein interactions are urgently needed. Such methods should connect multiple scales from e...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Gueudré, Thomas, Baldassi, Carlo, Zamparo, Marco, Weigt, Martin, Pagnani, Andrea
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2016
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087065/
https://ncbi.nlm.nih.gov/pubmed/27729520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1607570113
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